Basic Information
ID: ALA4386469
Type: Binding
Description: Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed by substrate addition by UV absorption analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Arachidonate 15-lipoxygenase(ALA2903)
Document: ALA4385612
Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 10 mins followed by substrate addition by UV absorption analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4386469
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.66 | 3.00 | 3.00 |
| 411.89 | 3.91 | 3.91 |
| 236.70 | 2.96 | 2.96 |
| 392.93 | 5.19 | 5.19 |
| 451.74 | 5.63 | 5.63 |
| 308.77 | 3.14 | 3.14 |
| 382.85 | 4.33 | 4.33 |
| 222.68 | 2.57 | 2.57 |
| 293.80 | 3.02 | 3.02 |
| 390.96 | 6.00 | 6.00 |
| 234.69 | 2.71 | 2.71 |
| 417.29 | 4.98 | 4.98 |
| 396.87 | 4.37 | 4.37 |
| 208.65 | 2.18 | 2.18 |
| 412.87 | 4.34 | 4.34 |
| 264.76 | 3.74 | 3.74 |
| 412.87 | 4.34 | 4.34 |
| 390.96 | 6.00 | 6.00 |
| 250.73 | 3.35 | 3.35 |
| 431.32 | 5.02 | 5.02 |
| 236.70 | 2.96 | 2.96 |
| 412.87 | 4.34 | 4.34 |
| 425.92 | 4.30 | 4.30 |
| 426.90 | 4.38 | 4.38 |
| 465.76 | 5.68 | 5.68 |