Basic Information
ID: ALA4386480
Type: Functional
Description: Decrease in c-KIT phosphorylation in NOD-SCID mouse xenografted with human GIST430 cells harboring c-KIT exon 11 primary in-frame V560-L576 deletion mutant and exon 13 heterozygous secondary missense V654A mutant at 80 mg/kg, po measured after 8 hrs by immunoblotting analysis relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4386480
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 519.64 | 4.68 | 4.68 |