Basic Information
ID: ALA4386485
Type: Binding
Description: Inhibition of recombinant human N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) expressed in baculovirus infected Sf9 insect cells assessed as decrease in poly (Glu,Tyr) 4:1 phosphorylation measured after 150 mins in presence of ATP by ADP-glo based luminescence assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4386485
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 500.63 | 5.05 | 5.05 |
| 533.66 | 4.99 | 4.99 |
| 505.61 | 4.38 | 4.38 |
| 535.70 | 4.59 | 4.59 |
| 535.63 | 3.65 | 3.65 |
| 533.66 | 4.99 | 4.99 |
| 519.64 | 4.68 | 4.68 |
| 523.67 | 4.00 | 4.00 |
| 533.66 | 4.99 | 4.99 |
| 520.62 | 4.08 | 4.08 |
| 423.55 | 3.44 | 3.44 |
| 424.53 | 2.98 | 2.98 |
| 534.65 | 4.38 | 4.38 |
| 499.65 | 3.43 | 3.43 |
| 481.59 | 2.54 | 2.54 |