Basic Information
ID: ALA4386539
Type: Binding
Description: Inhibition of c-KIT V560-L576 deletion/V654A double mutant phosphorylation in human GIST430 cells assessed as decrease in phosphorylation of AKT at 10 to 100 nM measured after 24 to 72 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: GIST430
Activity Charts
Bioactivity
Activity Types for Assay ALA4386539
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 519.64 | 4.68 | 4.68 |