Assay Report Card

Basic Information

ID: ALA4386550

Type: Functional

Description: Decrease in c-KIT phosphorylation in po dosed NOD-SCID mouse xenografted with human GIST430 cells harboring c-KIT exon 11 primary in-frame V560-L576 deletion mutant and exon 13 heterozygous secondary missense V654A mutant measured after 8 hrs by immunoblotting method

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
519.644.684.68