Basic Information
ID: ALA4386597
Type: Binding
Description: Inhibition of recombinant full length His-tagged HCV genotype 1b NS3/4A (1027 to 1657 residues) protease R155K (NS3) mutant expressed in Escherichia coli rosetta (DE3) cells using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis
Organism: Hepatitis C virus subtype 1b
Activity Charts
Bioactivity
Activity Types for Assay ALA4386597
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.99 | 5.62 | 5.62 |
| 499.62 | 5.91 | 5.91 |
| 492.41 | 5.96 | 5.96 |
| 518.45 | 6.48 | 6.48 |