Basic Information
ID: ALA4386801
Type: Binding
Description: Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC followed by washing with choline buffer and measured after 3 hrs by scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4386801
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 155.16 | -0.64 | -0.64 |
| 165.19 | 0.64 | 0.64 |
| 204.23 | 1.12 | 1.12 |
| 169.18 | -0.63 | -0.63 |
| 245.28 | 0.89 | 0.89 |
| 166.18 | 0.04 | 0.04 |
| 166.18 | 0.04 | 0.04 |
| 166.18 | 0.04 | 0.04 |
| 232.24 | 0.36 | 0.36 |
| 246.27 | 0.28 | 0.28 |
| 156.14 | -1.31 | -1.31 |
| 206.21 | -0.16 | -0.16 |
| 186.17 | -1.82 | -1.82 |
| 246.27 | 0.28 | 0.28 |
| 170.17 | -1.00 | -1.00 |
| 170.17 | -1.23 | -1.23 |