Basic Information
ID: ALA4386830
Type: Binding
Description: Inhibition of KIX-RLucN fused CBP (unknown origin) binding to KID-RLucC fused CREB (unknown origin) transfected in human HEK293 cells preincubated with compound 30 mins before before forskolin addition and measured after 90 mins in presence of coelenterazine by split Renilla luciferase complementation assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4386830
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 288.31 | 3.67 | 3.67 |
| 327.12 | 3.86 | 3.86 |
| 272.69 | 3.17 | 3.17 |
| 428.13 | 5.44 | 5.44 |
| 383.68 | 5.34 | 5.34 |
| 272.31 | 3.96 | 3.96 |
| 504.22 | 7.11 | 7.11 |
| 268.27 | 2.52 | 2.52 |
| 288.31 | 3.67 | 3.67 |
| 268.27 | 2.52 | 2.52 |
| 317.14 | 3.28 | 3.28 |
| 310.67 | 3.35 | 3.35 |