Basic Information
ID: ALA4387135
Type: ADME
Description: Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-BP1 as substrate preincubated for 30 mins followed by substrate addition and incubated for 90 mins by TR-FRET assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4387135
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.39 | 3.73 | 3.73 |
| 422.51 | 3.27 | 3.27 |
| 344.46 | 2.51 | 2.51 |
| 436.54 | 3.66 | 3.66 |
| 390.50 | 2.57 | 2.57 |
| 356.47 | 2.20 | 2.20 |
| 435.55 | 4.71 | 4.71 |
| 464.59 | 4.04 | 4.04 |
| 494.59 | 4.39 | 4.39 |
| 410.50 | 3.03 | 3.03 |
| 464.59 | 4.44 | 4.44 |
| 462.58 | 4.05 | 4.05 |
| 423.50 | 3.74 | 3.74 |
| 490.59 | 3.43 | 3.43 |
| 422.51 | 3.27 | 3.27 |
| 480.57 | 4.00 | 4.00 |
| 408.49 | 2.71 | 2.71 |
| 436.54 | 3.66 | 3.66 |
| 422.51 | 3.10 | 3.10 |
| 448.55 | 3.66 | 3.66 |