Assay Report Card

Basic Information

ID: ALA4387398

Type: Binding

Description: Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measuring dissociation constant for enzyme-inhibitor complex using L-arginine as substrate by Berthelot colorimetric method based Dixon/Cornish-Bowden plot analysis relative to control

Organism: Leishmania amazonensis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
924.090.710.71
333.343.193.19
320.302.282.28
319.312.882.88
334.332.582.58
284.312.572.57
318.323.053.05
338.744.034.03
304.303.383.38
387.313.903.90