Basic Information
ID: ALA4387563
Type: Binding
Description: Inhibition of 6x-His-tagged and SUMO tagged human PYCR1 expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in NADH oxidation incubated for 1 hr
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4387563
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 159.23 | 1.75 | 1.75 |
| 200.08 | 2.17 | 2.17 |
| 244.16 | 2.58 | 2.58 |
| 266.18 | 3.29 | 3.29 |
| 228.12 | 3.06 | 3.06 |
| 201.27 | 1.95 | 1.95 |
| 173.26 | 2.06 | 2.06 |
| 256.12 | 2.65 | 2.65 |
| 209.29 | 2.90 | 2.90 |
| 238.13 | 2.51 | 2.51 |
| 250.14 | 2.44 | 2.44 |
| 252.16 | 2.82 | 2.82 |
| 393.12 | 4.85 | 4.85 |
| 317.02 | 3.28 | 3.28 |
| 278.19 | 3.29 | 3.29 |
| 228.12 | 3.06 | 3.06 |
| 201.31 | 2.88 | 2.88 |
| 285.13 | 2.36 | 2.36 |
| 252.16 | 2.90 | 2.90 |
| 228.12 | 3.06 | 3.06 |
| 252.16 | 2.90 | 2.90 |
| 227.23 | 2.77 | 2.77 |
| 189.26 | 1.76 | 1.76 |
| 204.23 | 1.66 | 1.66 |
| 256.12 | 2.65 | 2.65 |
| 242.16 | 3.29 | 3.29 |
| 193.68 | 2.40 | 2.40 |
| 187.29 | 2.37 | 2.37 |
| 252.16 | 2.90 | 2.90 |
| 235.33 | 3.42 | 3.42 |
| 238.13 | 2.51 | 2.51 |
| 290.20 | 4.08 | 4.08 |
| 266.18 | 3.29 | 3.29 |
| 177.22 | 1.89 | 1.89 |
| 314.23 | 3.93 | 3.93 |
| 272.57 | 3.17 | 3.17 |
| 184.24 | 1.62 | 1.62 |
| 224.10 | 2.17 | 2.17 |
| 254.17 | 3.29 | 3.29 |
| 252.16 | 2.90 | 2.90 |
| 261.67 | 3.42 | 3.42 |
| 204.23 | 1.66 | 1.66 |
| 266.14 | 2.43 | 2.43 |
| 240.14 | 3.07 | 3.07 |
| 228.12 | 3.06 | 3.06 |
| 193.68 | 2.40 | 2.40 |
| 278.19 | 3.46 | 3.46 |
| 253.32 | 3.56 | 3.56 |
| 164.21 | 1.05 | 1.05 |
| 252.16 | 3.08 | 3.08 |
| 252.16 | 2.56 | 2.56 |
| 204.23 | 1.66 | 1.66 |
| 236.11 | 2.40 | 2.40 |
| 302.19 | 1.84 | 1.84 |
| 219.28 | 1.77 | 1.77 |
| 193.68 | 2.40 | 2.40 |
| 268.15 | 2.52 | 2.52 |
| 319.20 | 3.38 | 3.38 |
| 238.13 | 2.51 | 2.51 |
| 272.57 | 3.17 | 3.17 |
| 338.25 | 3.23 | 3.23 |