Basic Information
ID: ALA4387596
Type: Functional
Description: Antagonist activity at human OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincubated for 15 mins followed by orexin A addition by Fura 2-AM dye based fluorescence assay based by Cheng-Prusoff equation analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Orexin receptor 2(ALA4792)
Document: ALA4385659
Antagonist activity at human OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincubated for 15 mins followed by orexin A addition by Fura 2-AM dye based fluorescence assay based by Cheng-Prusoff equation analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4387596
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 590.74 | 4.85 | 4.85 |
| 574.74 | 5.74 | 5.74 |
| 588.73 | 5.11 | 5.11 |
| 604.73 | 4.22 | 4.22 |
| 604.73 | 4.22 | 4.22 |
| 588.73 | 5.11 | 5.11 |
| 574.74 | 5.74 | 5.74 |
| 590.74 | 4.85 | 4.85 |