Basic Information
ID: ALA4387632
Type: Functional
Description: Antagonist activity at human PTHR1 expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-induced cAMP accumulation incubated for 30 mins by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4387632
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.06 | 6.17 | 6.17 |
| 426.95 | 4.16 | 4.16 |
| 439.00 | 5.54 | 5.54 |
| 428.58 | 5.28 | 5.28 |
| 418.59 | 5.19 | 5.19 |
| 412.97 | 4.52 | 4.52 |
| 513.69 | 5.57 | 5.57 |
| 478.04 | 6.15 | 6.15 |
| 434.58 | 4.89 | 4.89 |
| 453.03 | 5.78 | 5.78 |
| 429.57 | 4.76 | 4.76 |
| 511.71 | 6.72 | 6.72 |
| 454.02 | 4.65 | 4.65 |
| 410.95 | 4.76 | 4.76 |
| 430.55 | 4.72 | 4.72 |
| 432.96 | 5.00 | 5.00 |
| 412.97 | 5.00 | 5.00 |
| 590.79 | 4.81 | 4.81 |
| 443.60 | 5.15 | 5.15 |
| 453.03 | 5.93 | 5.93 |