Basic Information
ID: ALA4387870
Type: Binding
Description: Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity by measuring bacterial killing at 64 ug/ml incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay relative to control
Format: BAO_0000357
Organism: Escherichia coli
Strain: isolate 3
Target: Metallo-beta-lactamase NDM-4(ALA4295642)
Document: ALA4387701
Inhibition of NDM4 in Escherichia coli isolate 3 assessed as potentiation of meropenem-induced bactericidal activity by measuring bacterial killing at 64 ug/ml incubated for 24 hrs followed by replating on agar plates for 16 to 18 hrs and measured up to 24 hrs by time kill assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4387870
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.34 | 0.75 | 0.75 |