Assay Report Card

Basic Information

ID: ALA4387890

Type: Binding

Description: Inhibition of MAPK/NFkappaB in ICR mouse RAW264.7 cells assessed as reduction in LPS-induced TNFalpha production at 10 uM pretreated for 0.5 hrs followed by LPS challenge and measured after 24 hrs by ELISA relative to control

Organism: Mus musculus

Strain: ICR

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
368.393.373.37
317.342.042.04
459.904.754.75
453.493.673.67
455.484.114.11
497.543.983.98
435.524.584.58
497.543.983.98
437.493.973.97
443.454.244.24
476.365.275.27
452.463.873.87
437.493.973.97
465.503.883.88
459.904.754.75
495.533.893.89
455.484.114.11
495.533.893.89
476.365.275.27
423.473.663.66
467.523.983.98
465.503.883.88
467.523.983.98
443.454.244.24