Basic Information
ID: ALA4387892
Type: Binding
Description: Inhibition of MAPK/NFkappaB in ICR mouse RAW264.7 cells assessed as reduction in LPS-induced IL6 production at 10 uM pretreated for 0.5 hrs followed by LPS challenge and measured after 24 hrs by ELISA relative to control
Organism: Mus musculus
Strain: ICR
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA4387892
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.37 | 3.37 |
| 317.34 | 2.04 | 2.04 |
| 459.90 | 4.75 | 4.75 |
| 453.49 | 3.67 | 3.67 |
| 455.48 | 4.11 | 4.11 |
| 497.54 | 3.98 | 3.98 |
| 435.52 | 4.58 | 4.58 |
| 497.54 | 3.98 | 3.98 |
| 437.49 | 3.97 | 3.97 |
| 443.45 | 4.24 | 4.24 |
| 476.36 | 5.27 | 5.27 |
| 452.46 | 3.87 | 3.87 |
| 437.49 | 3.97 | 3.97 |
| 465.50 | 3.88 | 3.88 |
| 459.90 | 4.75 | 4.75 |
| 495.53 | 3.89 | 3.89 |
| 455.48 | 4.11 | 4.11 |
| 495.53 | 3.89 | 3.89 |
| 476.36 | 5.27 | 5.27 |
| 423.47 | 3.66 | 3.66 |
| 467.52 | 3.98 | 3.98 |
| 465.50 | 3.88 | 3.88 |
| 467.52 | 3.98 | 3.98 |
| 443.45 | 4.24 | 4.24 |