Basic Information
ID: ALA4387937
Type: Functional
Description: Antiinflammatory activity in C57BL/6 mouse model of LPS-induced acute lung injury assessed as reduction in TNF-alpha mRNA expression in lung tissue at 10 mg/kg, ip administered daily for one week prior to LPS challenge and measured after 6 hrs by TRIZOL reagent-based RT-qPCR analysis
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4387937
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 453.49 | 3.67 | 3.67 |
| 495.53 | 3.89 | 3.89 |