Inhibition of human recombinant ALR2 expressed in Escherichia coli using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by ...

Basic Information

ID: ALA4388081

Type: Binding

Description: Inhibition of human recombinant ALR2 expressed in Escherichia coli using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured after 30 mins at 2 mins interval by spectrophotometry relative to control

Format: BAO_0000019

Organism: Homo sapiens

Target: Aldose reductase(ALA1900)

Document: ALA4387705

Inhibition of human recombinant ALR2 expressed in Escherichia coli using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured after 30 mins at 2 mins interval by spectrophotometry relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4388081

IC50

Total(18)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
236.20	0.64	0.64
319.41	2.92	2.92
374.39	2.30	2.30
398.48	3.28	3.28
374.39	2.30	2.30
398.44	2.36	2.36
390.85	2.81	2.81
390.85	2.81	2.81
386.43	2.17	2.17
370.43	2.47	2.47
398.48	3.28	3.28
401.40	2.07	2.07
401.40	2.07	2.07
370.43	2.47	2.47
398.44	2.36	2.36
386.43	2.17	2.17
435.30	2.92	2.92
435.30	2.92	2.92