Inhibition of rat kidney ALR1 using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured for 3...

Basic Information

ID: ALA4388083

Type: Binding

Description: Inhibition of rat kidney ALR1 using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured for 30 mins at 2 mins interval by spectrophotometry relative to control

Format: BAO_0000357

Organism: Rattus norvegicus

Target: Aldose reductase(ALA2622)

Document: ALA4387705

Inhibition of rat kidney ALR1 using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured for 30 mins at 2 mins interval by spectrophotometry relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4388083

IC50

Total(18)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
236.20	0.64	0.64
319.41	2.92	2.92
374.39	2.30	2.30
398.48	3.28	3.28
374.39	2.30	2.30
398.44	2.36	2.36
390.85	2.81	2.81
390.85	2.81	2.81
386.43	2.17	2.17
370.43	2.47	2.47
398.48	3.28	3.28
401.40	2.07	2.07
401.40	2.07	2.07
370.43	2.47	2.47
398.44	2.36	2.36
386.43	2.17	2.17
435.30	2.92	2.92
435.30	2.92	2.92