Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromato...

Basic Information

ID: ALA4388089

Type: Binding

Description: Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control

Format: BAO_0000219

Organism: Rattus norvegicus

Target: Aldose reductase(ALA2622)

Document: ALA4387705

Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4388089

IC50

Total(29)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
319.41	2.92	2.92
374.39	2.30	2.30
398.48	3.28	3.28
374.39	2.30	2.30
398.44	2.36	2.36
390.85	2.81	2.81
390.85	2.81	2.81
386.43	2.17	2.17
370.43	2.47	2.47
398.48	3.28	3.28
401.40	2.07	2.07
401.40	2.07	2.07
370.43	2.47	2.47
398.44	2.36	2.36
386.43	2.17	2.17
435.30	2.92	2.92
435.30	2.92	2.92