Basic Information
ID: ALA4388125
Type: Binding
Description: Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4388125
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.32 | 3.66 | 3.66 |
| 310.40 | 2.39 | 2.39 |
| 529.97 | 4.48 | 4.48 |
| 340.43 | 1.98 | 1.98 |
| 354.45 | 2.23 | 2.23 |
| 361.45 | 2.48 | 2.48 |
| 339.44 | 3.04 | 3.04 |
| 370.88 | 3.27 | 3.27 |
| 384.87 | 2.79 | 2.79 |
| 340.43 | 1.98 | 1.98 |
| 351.41 | 2.31 | 2.31 |
| 339.44 | 3.04 | 3.04 |
| 341.42 | 0.75 | 0.75 |
| 342.40 | 1.18 | 1.18 |
| 416.47 | 2.28 | 2.28 |
| 368.41 | 2.28 | 2.28 |
| 358.47 | 1.89 | 1.89 |
| 337.42 | 2.58 | 2.58 |
| 358.47 | 1.89 | 1.89 |
| 354.43 | 2.75 | 2.75 |
| 340.43 | 1.98 | 1.98 |
| 336.44 | 2.25 | 2.25 |
| 384.87 | 2.79 | 2.79 |
| 376.41 | 2.23 | 2.23 |
| 463.37 | 2.83 | 2.83 |
| 354.43 | 2.75 | 2.75 |
| 375.43 | 2.01 | 2.01 |
| 342.40 | 1.18 | 1.18 |
| 419.31 | 3.45 | 3.45 |
| 370.88 | 3.27 | 3.27 |
| 337.42 | 2.95 | 2.95 |
| 376.41 | 2.23 | 2.23 |
| 336.44 | 2.61 | 2.61 |
| 428.92 | 2.18 | 2.18 |
| 350.42 | 1.89 | 1.89 |
| 356.47 | 2.25 | 2.25 |
| 368.41 | 2.28 | 2.28 |
| 405.33 | 3.92 | 3.92 |
| 368.48 | 2.62 | 2.62 |
| 386.40 | 2.42 | 2.42 |
| 372.42 | 2.89 | 2.89 |
| 414.94 | 2.65 | 2.65 |
| 358.47 | 1.89 | 1.89 |
| 355.44 | 1.09 | 1.09 |
| 394.48 | 1.53 | 1.53 |
| 337.42 | 2.67 | 2.67 |
| 430.46 | 1.80 | 1.80 |
| 350.42 | 2.14 | 2.14 |
| 374.47 | 0.91 | 0.91 |
| 415.34 | 3.37 | 3.37 |
| 398.48 | 2.14 | 2.14 |
| 429.32 | 2.90 | 2.90 |
| 351.41 | 2.11 | 2.11 |
| 412.47 | 1.66 | 1.66 |
| 380.49 | 2.00 | 2.00 |
| 354.45 | 2.37 | 2.37 |
| 449.38 | 3.31 | 3.31 |