Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase...

Basic Information

ID: ALA4388125

Type: Binding

Description: Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase reporter gene assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  Tankyrase 1/2(ALA3038515)

Document:  ALA4387706

Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase reporter gene assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
312.323.663.66
310.402.392.39
529.974.484.48
340.431.981.98
354.452.232.23
361.452.482.48
339.443.043.04
370.883.273.27
384.872.792.79
340.431.981.98
351.412.312.31
339.443.043.04
341.420.750.75
342.401.181.18
416.472.282.28
368.412.282.28
358.471.891.89
337.422.582.58
358.471.891.89
354.432.752.75
340.431.981.98
336.442.252.25
384.872.792.79
376.412.232.23
463.372.832.83
354.432.752.75
375.432.012.01
342.401.181.18
419.313.453.45
370.883.273.27
337.422.952.95
376.412.232.23
336.442.612.61
428.922.182.18
350.421.891.89
356.472.252.25
368.412.282.28
405.333.923.92
368.482.622.62
386.402.422.42
372.422.892.89
414.942.652.65
358.471.891.89
355.441.091.09
394.481.531.53
337.422.672.67
430.461.801.80
350.422.142.14
374.470.910.91
415.343.373.37
398.482.142.14
429.322.902.90
351.412.112.11
412.471.661.66
380.492.002.00
354.452.372.37
449.383.313.31