Basic Information
ID: ALA4388217
Type: Binding
Description: Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR method
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4388217
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 618.56 | 7.24 | 7.24 |
| 572.49 | 4.98 | 4.98 |
| 634.56 | 6.95 | 6.95 |
| 634.56 | 7.60 | 7.60 |
| 619.55 | 6.63 | 6.63 |
| 660.60 | 7.44 | 7.44 |
| 634.56 | 6.95 | 6.95 |
| 648.59 | 7.25 | 7.25 |
| 544.44 | 5.90 | 5.90 |
| 619.55 | 6.63 | 6.63 |
| 624.59 | 7.30 | 7.30 |
| 514.45 | 5.57 | 5.57 |
| 572.49 | 4.98 | 4.98 |
| 619.55 | 6.63 | 6.63 |
| 582.49 | 4.86 | 4.86 |
| 619.55 | 6.63 | 6.63 |
| 619.55 | 6.63 | 6.63 |
| 634.56 | 7.60 | 7.60 |
| 608.52 | 6.83 | 6.83 |
| 634.56 | 6.95 | 6.95 |
| 668.62 | 8.39 | 8.39 |
| 668.62 | 8.39 | 8.39 |
| 653.01 | 7.89 | 7.89 |
| 618.56 | 7.24 | 7.24 |
| 634.56 | 6.95 | 6.95 |
| 582.49 | 4.86 | 4.86 |
| 544.44 | 5.90 | 5.90 |
| 634.56 | 6.95 | 6.95 |
| 619.55 | 6.63 | 6.63 |
| 634.56 | 6.95 | 6.95 |
| 514.45 | 5.57 | 5.57 |