Basic Information
ID: ALA4388229
Type: Binding
Description: Inhibition of N-terminal His-tagged Trypanosoma brucei pteridine reductase 1 using di-hydrobiopterine as substrate measured at 1 min interval for 50 mins in presence of NADPH
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA4388229
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.72 | 2.52 | 2.52 |
| 234.20 | 2.78 | 2.78 |
| 250.27 | 3.49 | 3.49 |
| 228.30 | 1.28 | 1.28 |
| 256.33 | 3.46 | 3.46 |
| 359.45 | 4.40 | 4.40 |
| 341.29 | 5.48 | 5.48 |
| 304.40 | 2.85 | 2.85 |
| 441.58 | 4.20 | 4.20 |
| 442.37 | 6.03 | 6.03 |
| 362.43 | 2.64 | 2.64 |
| 452.54 | 2.83 | 2.83 |
| 327.41 | 2.51 | 2.51 |
| 384.24 | 3.53 | 3.53 |
| 315.35 | 2.22 | 2.22 |
| 352.25 | 4.12 | 4.12 |
| 298.37 | 2.39 | 2.39 |
| 502.42 | 6.05 | 6.05 |
| 329.41 | 2.72 | 2.72 |
| 325.22 | 4.76 | 4.76 |
| 281.34 | 3.33 | 3.33 |
| 283.36 | 2.81 | 2.81 |
| 272.40 | 4.17 | 4.17 |
| 473.58 | 2.88 | 2.88 |
| 336.42 | 3.33 | 3.33 |
| 314.37 | 3.24 | 3.24 |
| 303.41 | 2.91 | 2.91 |
| 308.37 | 2.68 | 2.68 |
| 405.55 | 5.10 | 5.10 |
| 297.41 | 4.04 | 4.04 |
| 425.51 | 3.48 | 3.48 |
| 330.43 | 3.96 | 3.96 |
| 341.39 | 2.60 | 2.60 |
| 416.51 | 3.74 | 3.74 |
| 328.35 | 2.72 | 2.72 |
| 474.37 | 5.44 | 5.44 |