Basic Information
ID: ALA4388236
Type: Functional
Description: Inhibition of PTR1 in Trypanosoma brucei bloodstream forms assessed as potentiation of methotrexate-induced parasitic cell growth inhibition by measuring potentiation index at 10 uM measured after 72 hrs by resazurin-based fluorescence assay relative to control (methotrexate)
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA4388236
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 250.27 | 3.49 | 3.49 |
| 341.29 | 5.48 | 5.48 |
| 441.58 | 4.20 | 4.20 |
| 329.41 | 2.72 | 2.72 |
| 325.22 | 4.76 | 4.76 |
| 281.34 | 3.33 | 3.33 |
| 283.36 | 2.81 | 2.81 |
| 405.55 | 5.10 | 5.10 |
| 297.41 | 4.04 | 4.04 |
| 330.43 | 3.96 | 3.96 |