Basic Information
ID: ALA4388470
Type: ADME
Description: Inhibition of recombinant bovine enterokinase activated N-terminal His-tagged recombinant human KLK1 (19 to 262 residues) expressed in baculovirus infected Sf9 insect cells using 3',6'-bis(prolylphenylalanylarginylamino)3H-spiro(2-benzofuran-1,9'-xanthen)-3-one;TFA as substrate measured at 30 secs interval for 5 mins by fluorescence intensity assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4388470
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.50 | 2.88 | 2.88 |
| 387.87 | 2.34 | 2.34 |
| 291.36 | 2.97 | 2.97 |
| 375.48 | 4.15 | 4.15 |
| 279.35 | 2.47 | 2.47 |
| 378.48 | 2.91 | 2.91 |
| 404.47 | 2.63 | 2.63 |
| 293.33 | 2.11 | 2.11 |
| 336.23 | 3.11 | 3.11 |
| 431.93 | 5.21 | 5.21 |
| 251.72 | 1.31 | 1.31 |
| 409.49 | 4.01 | 4.01 |
| 424.46 | 2.10 | 2.10 |
| 407.47 | 3.76 | 3.76 |
| 431.93 | 5.21 | 5.21 |
| 265.75 | 1.32 | 1.32 |
| 434.93 | 3.95 | 3.95 |
| 410.43 | 1.84 | 1.84 |
| 398.47 | 3.95 | 3.95 |
| 397.48 | 4.55 | 4.55 |
| 325.37 | 2.77 | 2.77 |
| 295.35 | 2.47 | 2.47 |
| 381.44 | 3.37 | 3.37 |
| 435.92 | 3.34 | 3.34 |
| 431.93 | 5.21 | 5.21 |
| 265.32 | 2.46 | 2.46 |
| 388.43 | 3.54 | 3.54 |