Basic Information
ID: ALA4388507
Type: Toxicity
Description: Toxicity in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant assessed as change in body weight at 30 mg/kg, po administered once daily for 14 days and measured twice per week for 14 days during compound dosing
Format: BAO_0000218
Organism: Mus musculus
Target: ADMET(ALA612558)
Document: ALA4387718
Toxicity in SCID Beige nude mouse xenografted with human NCI-H2228 cells harboring EML4-fused ALK variant assessed as change in body weight at 30 mg/kg, po administered once daily for 14 days and measured twice per week for 14 days during compound dosing: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4388507
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 533.11 | 5.58 | 5.58 |