Basic Information
ID: ALA4388565
Type: Binding
Description: Reversible inhibition of human partial length EGFR L858R mutant (R669 to V1011 residues) expressed in bacterial expression system assessed as ratio of Kd under under partial equilibration condition to under full equilibrating condition by scanKINETIC assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4387720
Reversible inhibition of human partial length EGFR L858R mutant (R669 to V1011 residues) expressed in bacterial expression system assessed as ratio of Kd under under partial equilibration condition to under full equilibrating condition by scanKINETIC assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4388565
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 727.24 | 6.07 | 6.07 |
| 641.15 | 5.90 | 5.90 |