Basic Information
ID: ALA4388637
Type: Binding
Description: Inhibition of human PTPN5 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric method
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein phosphatase non-receptor type 5(ALA2007628)
Document: ALA4387722
Inhibition of human PTPN5 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4388637
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 533.63 | 5.71 | 5.71 |
| 350.40 | 4.30 | 4.30 |
| 532.65 | 5.45 | 5.45 |
| 533.63 | 5.71 | 5.71 |
| 381.44 | 2.24 | 2.24 |
| 541.56 | 5.37 | 5.37 |
| 641.57 | 7.13 | 7.13 |
| 505.58 | 5.10 | 5.10 |
| 574.47 | 6.40 | 6.40 |
| 555.60 | 4.84 | 4.84 |
| 593.60 | 4.49 | 4.49 |
| 641.57 | 7.13 | 7.13 |
| 537.58 | 4.51 | 4.51 |
| 621.71 | 5.11 | 5.11 |
| 541.56 | 5.37 | 5.37 |
| 555.60 | 4.84 | 4.84 |
| 533.63 | 5.38 | 5.38 |
| 565.63 | 5.11 | 5.11 |
| 541.56 | 5.37 | 5.37 |
| 593.60 | 4.49 | 4.49 |
| 641.64 | 5.31 | 5.31 |
| 595.57 | 4.91 | 4.91 |
| 621.65 | 4.67 | 4.67 |
| 555.60 | 4.84 | 4.84 |
| 605.70 | 7.40 | 7.40 |
| 437.54 | 3.80 | 3.80 |
| 537.58 | 4.51 | 4.51 |
| 663.37 | 6.62 | 6.62 |
| 535.61 | 4.26 | 4.26 |
| 589.57 | 4.17 | 4.17 |
| 565.63 | 5.11 | 5.11 |
| 533.63 | 5.71 | 5.71 |
| 619.73 | 6.32 | 6.32 |
| 621.65 | 4.67 | 4.67 |
| 489.38 | 4.02 | 4.02 |
| 535.61 | 4.26 | 4.26 |
| 595.57 | 4.91 | 4.91 |
| 621.65 | 4.67 | 4.67 |
| 595.57 | 4.91 | 4.91 |
| 641.57 | 7.13 | 7.13 |
| 517.64 | 5.22 | 5.22 |
| 574.47 | 6.40 | 6.40 |
| 593.60 | 4.49 | 4.49 |
| 565.63 | 5.11 | 5.11 |
| 663.37 | 6.62 | 6.62 |
| 621.71 | 5.11 | 5.11 |
| 663.37 | 6.62 | 6.62 |
| 574.47 | 6.40 | 6.40 |
| 537.58 | 4.51 | 4.51 |
| 614.05 | 6.83 | 6.83 |
| 648.49 | 7.48 | 7.48 |
| 625.49 | 6.37 | 6.37 |
| 586.53 | 6.53 | 6.53 |
| 614.94 | 7.12 | 7.12 |
| 625.49 | 6.37 | 6.37 |
| 588.05 | 5.35 | 5.35 |
| 575.09 | 5.27 | 5.27 |
| 648.49 | 7.48 | 7.48 |
| 605.70 | 7.40 | 7.40 |
| 575.09 | 5.27 | 5.27 |
| 614.05 | 6.83 | 6.83 |
| 546.05 | 5.81 | 5.81 |
| 384.84 | 4.95 | 4.95 |
| 588.05 | 5.35 | 5.35 |
| 552.08 | 5.87 | 5.87 |
| 384.84 | 4.95 | 4.95 |
| 610.52 | 6.47 | 6.47 |
| 574.11 | 6.37 | 6.37 |
| 614.08 | 5.92 | 5.92 |
| 596.11 | 6.96 | 6.96 |
| 418.40 | 5.31 | 5.31 |
| 418.40 | 5.31 | 5.31 |
| 552.08 | 5.87 | 5.87 |
| 614.08 | 5.92 | 5.92 |
| 384.84 | 4.95 | 4.95 |
| 624.95 | 6.57 | 6.57 |
| 596.11 | 6.96 | 6.96 |
| 546.05 | 5.81 | 5.81 |
| 576.08 | 5.82 | 5.82 |
| 610.52 | 6.47 | 6.47 |
| 632.04 | 6.97 | 6.97 |
| 596.11 | 6.96 | 6.96 |
| 576.08 | 5.82 | 5.82 |
| 572.09 | 6.45 | 6.45 |
| 483.98 | 4.38 | 4.38 |
| 368.39 | 4.43 | 4.43 |
| 614.94 | 7.12 | 7.12 |
| 356.43 | 4.36 | 4.36 |
| 603.13 | 6.42 | 6.42 |
| 632.04 | 6.97 | 6.97 |
| 624.95 | 6.57 | 6.57 |
| 572.09 | 6.45 | 6.45 |
| 368.39 | 4.43 | 4.43 |
| 368.39 | 4.43 | 4.43 |
| 603.13 | 6.42 | 6.42 |
| 390.87 | 5.01 | 5.01 |
| 483.98 | 4.38 | 4.38 |
| 574.11 | 6.37 | 6.37 |
| 288.33 | 2.87 | 2.87 |
| 596.11 | 6.96 | 6.96 |