Basic Information
ID: ALA4388642
Type: Binding
Description: Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric analysis
Format: BAO_0000019
Organism: Escherichia coli
Target: GroEL/GroES(ALA4106139)
Document: ALA4387722
Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4388642
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.40 | 4.30 | 4.30 |
| 350.40 | 4.30 | 4.30 |
| 364.43 | 4.60 | 4.60 |
| 436.39 | 5.45 | 5.45 |
| 384.84 | 4.95 | 4.95 |
| 384.84 | 4.95 | 4.95 |
| 356.43 | 4.36 | 4.36 |
| 364.43 | 4.60 | 4.60 |
| 384.84 | 4.95 | 4.95 |
| 368.39 | 4.43 | 4.43 |
| 380.43 | 4.30 | 4.30 |
| 418.40 | 5.31 | 5.31 |
| 429.84 | 4.86 | 4.86 |
| 380.43 | 4.30 | 4.30 |
| 380.43 | 4.30 | 4.30 |
| 364.43 | 4.60 | 4.60 |
| 378.45 | 4.86 | 4.86 |
| 376.44 | 4.94 | 4.94 |
| 380.43 | 4.30 | 4.30 |
| 366.40 | 4.00 | 4.00 |
| 366.40 | 4.00 | 4.00 |
| 288.33 | 2.87 | 2.87 |
| 418.40 | 5.31 | 5.31 |
| 436.39 | 5.45 | 5.45 |
| 364.43 | 4.60 | 4.60 |
| 418.40 | 5.31 | 5.31 |
| 390.87 | 5.01 | 5.01 |
| 366.40 | 4.00 | 4.00 |
| 368.39 | 4.43 | 4.43 |
| 366.40 | 4.00 | 4.00 |
| 418.40 | 5.31 | 5.31 |
| 384.84 | 4.95 | 4.95 |
| 418.40 | 5.31 | 5.31 |
| 378.45 | 4.86 | 4.86 |
| 368.39 | 4.43 | 4.43 |
| 356.43 | 4.36 | 4.36 |
| 414.87 | 4.96 | 4.96 |
| 384.84 | 4.95 | 4.95 |
| 429.84 | 4.86 | 4.86 |
| 380.43 | 4.30 | 4.30 |
| 380.43 | 4.30 | 4.30 |
| 452.84 | 5.97 | 5.97 |
| 368.39 | 4.43 | 4.43 |
| 419.29 | 5.60 | 5.60 |
| 364.43 | 4.60 | 4.60 |
| 368.39 | 4.43 | 4.43 |
| 419.29 | 5.60 | 5.60 |
| 368.39 | 4.43 | 4.43 |
| 390.87 | 5.01 | 5.01 |
| 366.40 | 4.00 | 4.00 |
| 414.87 | 4.96 | 4.96 |
| 366.40 | 4.00 | 4.00 |
| 452.84 | 5.97 | 5.97 |
| 376.44 | 4.94 | 4.94 |
| 418.40 | 5.31 | 5.31 |
| 384.84 | 4.95 | 4.95 |
| 288.33 | 2.87 | 2.87 |
| 364.43 | 4.60 | 4.60 |