Basic Information
ID: ALA4388644
Type: Binding
Description: Inhibition of human HSP60 expressed in Escherichia coli Rosetta 2(DE3)/human HSP10 expressed in Escherichia coli Rosetta 2(DE3) pLysS cells assessed as reduction in HSP60/HSP10-mediated denatured pig heart mitochondrial MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 40 to 60 mins by spectrometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4388644
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.40 | 4.30 | 4.30 |
| 350.40 | 4.30 | 4.30 |
| 505.58 | 5.10 | 5.10 |
| 555.60 | 4.84 | 4.84 |
| 537.58 | 4.51 | 4.51 |
| 541.56 | 5.37 | 5.37 |
| 541.56 | 5.37 | 5.37 |
| 537.58 | 4.51 | 4.51 |
| 517.64 | 5.22 | 5.22 |
| 537.58 | 4.51 | 4.51 |
| 588.05 | 5.35 | 5.35 |
| 575.09 | 5.27 | 5.27 |
| 575.09 | 5.27 | 5.27 |
| 364.43 | 4.60 | 4.60 |
| 436.39 | 5.45 | 5.45 |
| 546.05 | 5.81 | 5.81 |
| 384.84 | 4.95 | 4.95 |
| 384.84 | 4.95 | 4.95 |
| 356.43 | 4.36 | 4.36 |
| 364.43 | 4.60 | 4.60 |
| 384.84 | 4.95 | 4.95 |
| 368.39 | 4.43 | 4.43 |
| 380.43 | 4.30 | 4.30 |
| 418.40 | 5.31 | 5.31 |
| 429.84 | 4.86 | 4.86 |
| 380.43 | 4.30 | 4.30 |
| 380.43 | 4.30 | 4.30 |
| 364.43 | 4.60 | 4.60 |
| 378.45 | 4.86 | 4.86 |
| 376.44 | 4.94 | 4.94 |
| 380.43 | 4.30 | 4.30 |
| 366.40 | 4.00 | 4.00 |
| 366.40 | 4.00 | 4.00 |
| 288.33 | 2.87 | 2.87 |
| 418.40 | 5.31 | 5.31 |
| 436.39 | 5.45 | 5.45 |
| 364.43 | 4.60 | 4.60 |
| 418.40 | 5.31 | 5.31 |
| 552.08 | 5.87 | 5.87 |
| 390.87 | 5.01 | 5.01 |
| 366.40 | 4.00 | 4.00 |
| 368.39 | 4.43 | 4.43 |
| 366.40 | 4.00 | 4.00 |
| 418.40 | 5.31 | 5.31 |
| 384.84 | 4.95 | 4.95 |
| 418.40 | 5.31 | 5.31 |
| 378.45 | 4.86 | 4.86 |
| 368.39 | 4.43 | 4.43 |
| 356.43 | 4.36 | 4.36 |
| 414.87 | 4.96 | 4.96 |
| 384.84 | 4.95 | 4.95 |
| 429.84 | 4.86 | 4.86 |
| 380.43 | 4.30 | 4.30 |
| 380.43 | 4.30 | 4.30 |
| 452.84 | 5.97 | 5.97 |
| 368.39 | 4.43 | 4.43 |
| 419.29 | 5.60 | 5.60 |
| 364.43 | 4.60 | 4.60 |
| 368.39 | 4.43 | 4.43 |
| 419.29 | 5.60 | 5.60 |
| 368.39 | 4.43 | 4.43 |
| 390.87 | 5.01 | 5.01 |
| 366.40 | 4.00 | 4.00 |
| 414.87 | 4.96 | 4.96 |
| 366.40 | 4.00 | 4.00 |
| 452.84 | 5.97 | 5.97 |
| 483.98 | 4.38 | 4.38 |
| 376.44 | 4.94 | 4.94 |
| 418.40 | 5.31 | 5.31 |
| 384.84 | 4.95 | 4.95 |
| 288.33 | 2.87 | 2.87 |
| 364.43 | 4.60 | 4.60 |