Basic Information
ID: ALA4388891
Type: Functional
Description: Positive allosteric modulation of recombinant human GPR40 expressed in HEK293 cells assessed as increase in [3H]-myo-inositol phosphate accumulation measured after 60 mins in absence of human serum by microbeta counting method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4388891
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.48 | 6.05 | 6.05 |
| 514.64 | 8.25 | 8.25 |
| 478.54 | 6.92 | 6.92 |
| 460.55 | 6.78 | 6.78 |
| 478.54 | 6.92 | 6.92 |
| 461.53 | 6.18 | 6.18 |
| 460.55 | 6.78 | 6.78 |
| 554.70 | 8.99 | 8.99 |
| 446.52 | 6.54 | 6.54 |
| 479.52 | 6.32 | 6.32 |
| 464.51 | 6.68 | 6.68 |
| 448.49 | 5.98 | 5.98 |
| 443.54 | 6.04 | 6.04 |
| 460.55 | 6.78 | 6.78 |
| 461.53 | 6.18 | 6.18 |
| 461.53 | 6.18 | 6.18 |
| 461.53 | 6.18 | 6.18 |
| 478.54 | 6.92 | 6.92 |