Basic Information
ID: ALA4388991
Type: Binding
Description: Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG fluorescent peptide addition in presence of 20 uM ADP followed by further incubation for 2 hrs by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4388991
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.91 | 6.61 | 6.61 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 338.02 | 5.30 | 5.30 |
| 289.55 | 5.14 | 5.14 |
| 200.24 | 2.69 | 2.69 |
| 340.51 | 5.90 | 5.90 |
| 401.46 | 5.62 | 5.62 |
| 368.56 | 6.41 | 6.41 |
| 424.95 | 7.17 | 7.17 |