Basic Information
ID: ALA4390080
Type: Binding
Description: Positive allosteric modulation activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel current at 0.1 uM to 30 uM at -90 mV holding potential preincubated for 2 mins followed by co-application with acetylcholine for 10 secs by two-electrode voltage clamp method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4390080
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.83 | 4.99 | 4.99 |