ID: ALA4390082
Type: Binding
Description: Positive allosteric modulation activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel current by measuring acetylcholine EC50 at 10 uM at -90 mV holding potential preincubated for 2 mins followed by co-application with acetylcholine for 10 secs by two-electrode voltage clamp method (Rvb = 231.8 +/- 2 uM)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4390082
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
369.83 | 4.99 | 4.99 |