Basic Information
ID: ALA4390087
Type: Binding
Description: Positive allosteric modulation activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as increase in acetylcholine-induced channel current at 10 uM at -90 mV holding potential preincubated for 2 mins followed by co-application with acetylcholine for 10 secs by two-electrode voltage clamp method relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4390087
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.83 | 4.99 | 4.99 |