Metabolic stability assessed as trypsin (unknown origin)-mediated drug degradation by measuring half life in pH 7.5 Tris buffer incubated up to 60 min...

Basic Information

ID: ALA4390130

Type: ADME

Description: Metabolic stability assessed as trypsin (unknown origin)-mediated drug degradation by measuring half life in pH 7.5 Tris buffer incubated up to 60 mins at 37 degC by HPLC and UV analysis

Format: BAO_0000224

Organism: Homo sapiens

Target:  Trypsin(ALA2095204)

Document:  ALA4387750

Metabolic stability assessed as trypsin (unknown origin)-mediated drug degradation by measuring half life in pH 7.5 Tris buffer incubated up to 60 mins at 37 degC by HPLC and UV analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
538.650.000.00
644.781.581.58
552.680.180.18
630.75-0.05-0.05
552.680.350.35