Basic Information
ID: ALA4390132
Type: ADME
Description: Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using 18 uM DHFA as substrate
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4390132
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 325.37 | 2.11 | 2.11 |
| 369.43 | 2.74 | 2.74 |
| 252.28 | 1.93 | 1.93 |
| 282.31 | 1.94 | 1.94 |
| 266.31 | 2.24 | 2.24 |
| 302.34 | 3.09 | 3.09 |
| 302.34 | 3.09 | 3.09 |
| 306.25 | 2.35 | 2.35 |