Basic Information
ID: ALA4390135
Type: Toxicity
Description: Selectivity ratio of IC50 for inhibition of recombinant human DHFR using 18 uM DHFA as substrate to IC50 for inhibition of Pneumocystis jirovecii DHFR using 18 uM DHFA as substrate
Activity Charts
Bioactivity
Activity Types for Assay ALA4390135
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 325.37 | 2.11 | 2.11 |
| 369.43 | 2.74 | 2.74 |
| 252.28 | 1.93 | 1.93 |
| 282.31 | 1.94 | 1.94 |
| 266.31 | 2.24 | 2.24 |
| 302.34 | 3.09 | 3.09 |
| 302.34 | 3.09 | 3.09 |
| 306.25 | 2.35 | 2.35 |