Basic Information
ID: ALA4390175
Type: ADME
Description: Ratio of Cmin in C57BL/6 mouse at 20 mg/kg, po bid measured after 8 hrs to IC50 for inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by LC/MS analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4390175
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.58 | 1.99 | 1.99 |