Basic Information
ID: ALA4390245
Type: Binding
Description: Inhibition of N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in presence of NADPH incubated for 40 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Isocitrate dehydrogenase [NADP] cytoplasmic(ALA2007625)
Document: ALA4387756
Inhibition of N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in presence of NADPH incubated for 40 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390245
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.55 | 4.80 | 4.80 |
| 462.57 | 4.86 | 4.86 |
| 463.71 | 6.42 | 6.42 |
| 411.66 | 7.54 | 7.54 |
| 437.67 | 5.89 | 5.89 |
| 423.65 | 5.50 | 5.50 |
| 366.55 | 5.10 | 5.10 |
| 437.67 | 5.89 | 5.89 |
| 435.66 | 5.50 | 5.50 |
| 395.59 | 6.82 | 6.82 |
| 396.58 | 5.11 | 5.11 |
| 457.66 | 6.29 | 6.29 |
| 409.62 | 5.11 | 5.11 |
| 399.55 | 5.55 | 5.55 |
| 396.58 | 5.11 | 5.11 |
| 395.59 | 4.72 | 4.72 |
| 379.59 | 5.01 | 5.01 |