Basic Information
ID: ALA4390253
Type: Binding
Description: Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as induction of differentiation by measuring decrease in SOX2 mRNA expression at 1 umol/L after 6 days by qRT-PCR analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Isocitrate dehydrogenase [NADP] cytoplasmic(ALA2007625)
Document: ALA4387756
Inhibition of IDH1 R132C mutant in human HT1080 cells assessed as induction of differentiation by measuring decrease in SOX2 mRNA expression at 1 umol/L after 6 days by qRT-PCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390253
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.55 | 4.80 | 4.80 |