Basic Information
ID: ALA4390349
Type: Binding
Description: Inhibition of FITSI-labelled BID binding to human MCl-1 (171 to 327 residues) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Induced myeloid leukemia cell differentiation protein Mcl-1(ALA4361)
Document: ALA4387763
Inhibition of FITSI-labelled BID binding to human MCl-1 (171 to 327 residues) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390349
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.07 | 5.10 | 5.10 |
| 352.24 | 4.95 | 4.95 |
| 571.01 | 4.76 | 4.76 |
| 445.81 | 3.14 | 3.14 |
| 623.07 | 6.62 | 6.62 |
| 456.85 | 3.34 | 3.34 |
| 413.83 | 4.32 | 4.32 |
| 593.09 | 7.11 | 7.11 |
| 561.00 | 5.30 | 5.30 |
| 529.01 | 5.82 | 5.82 |
| 546.98 | 4.96 | 4.96 |
| 410.65 | 5.53 | 5.53 |
| 361.21 | 4.01 | 4.01 |
| 349.76 | 4.47 | 4.47 |
| 595.06 | 7.29 | 7.29 |
| 482.89 | 3.88 | 3.88 |
| 545.99 | 4.36 | 4.36 |
| 624.08 | 3.95 | 3.95 |
| 561.00 | 5.35 | 5.35 |
| 547.96 | 4.35 | 4.35 |
| 502.97 | 5.50 | 5.50 |
| 498.93 | 4.37 | 4.37 |
| 686.16 | 5.38 | 5.38 |
| 480.88 | 2.97 | 2.97 |
| 586.01 | 5.44 | 5.44 |
| 536.94 | 3.68 | 3.68 |
| 367.75 | 4.61 | 4.61 |
| 590.05 | 3.98 | 3.98 |
| 292.15 | 2.52 | 2.52 |
| 452.39 | 3.11 | 3.11 |
| 518.97 | 4.99 | 4.99 |
| 420.80 | 3.80 | 3.80 |
| 367.75 | 4.61 | 4.61 |
| 336.63 | 4.45 | 4.45 |
| 344.26 | 4.92 | 4.92 |
| 476.91 | 3.22 | 3.22 |
| 612.05 | 4.68 | 4.68 |
| 339.73 | 2.89 | 2.89 |
| 405.52 | 5.75 | 5.75 |
| 404.62 | 5.47 | 5.47 |
| 546.98 | 4.96 | 4.96 |
| 577.00 | 4.93 | 4.93 |
| 510.94 | 4.61 | 4.61 |
| 370.18 | 4.81 | 4.81 |
| 363.79 | 4.78 | 4.78 |
| 561.00 | 5.04 | 5.04 |
| 579.07 | 7.24 | 7.24 |
| 388.20 | 3.85 | 3.85 |
| 370.18 | 4.81 | 4.81 |
| 546.98 | 4.96 | 4.96 |
| 470.88 | 3.73 | 3.73 |
| 371.07 | 5.10 | 5.10 |
| 404.62 | 5.47 | 5.47 |
| 470.88 | 3.73 | 3.73 |
| 518.97 | 4.99 | 4.99 |