Basic Information
ID: ALA4390460
Type: Binding
Description: Inverse agonist activity at human Gal4-fused RORalpha LBD (272 to 556 residues) expressed in human Jurkat cells measured after 18 hrs by steady-glo luciferase reporter gene assay
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA4390460
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 651.57 | 4.93 | 4.93 |
| 661.63 | 5.62 | 5.62 |
| 626.57 | 5.31 | 5.31 |
| 625.53 | 5.37 | 5.37 |
| 667.58 | 4.79 | 4.79 |
| 655.56 | 5.43 | 5.43 |
| 633.58 | 4.84 | 4.84 |
| 645.54 | 6.00 | 6.00 |
| 599.54 | 5.57 | 5.57 |
| 645.54 | 6.00 | 6.00 |
| 627.55 | 5.91 | 5.91 |
| 669.63 | 7.08 | 7.08 |
| 661.63 | 5.62 | 5.62 |
| 649.58 | 3.96 | 3.96 |
| 619.55 | 4.45 | 4.45 |
| 655.60 | 6.69 | 6.69 |
| 641.58 | 6.00 | 6.00 |
| 643.55 | 5.02 | 5.02 |
| 663.61 | 4.61 | 4.61 |
| 625.53 | 5.37 | 5.37 |
| 641.58 | 6.30 | 6.30 |
| 663.61 | 4.20 | 4.20 |
| 625.53 | 5.37 | 5.37 |
| 639.56 | 6.05 | 6.05 |
| 653.59 | 6.44 | 6.44 |
| 655.60 | 6.69 | 6.69 |
| 655.56 | 5.43 | 5.43 |
| 645.54 | 6.00 | 6.00 |
| 613.57 | 5.82 | 5.82 |
| 647.61 | 5.23 | 5.23 |
| 651.58 | 5.50 | 5.50 |
| 671.60 | 5.92 | 5.92 |
| 641.58 | 6.30 | 6.30 |
| 657.58 | 5.68 | 5.68 |
| 641.58 | 6.30 | 6.30 |