Basic Information
ID: ALA4390488
Type: Binding
Description: Inhibition of TRAF6 (unknown origin)-mediated NFkappaB activation expressed in human HeLaS3 cells harboring 3kappaB-tk-luc at 10 uM preincubated for 1 hr followed by Il1alpha-stimulation and measured after 3 hrs in presence of DTT by dual-luciferase reporter gene assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4390488
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 641.93 | 3.07 | 3.07 |
| 520.81 | 6.09 | 6.09 |
| 484.78 | 5.59 | 5.59 |
| 563.75 | 5.96 | 5.96 |
| 155.18 | 1.88 | 1.88 |
| 606.82 | 6.02 | 6.02 |
| 562.76 | 6.56 | 6.56 |
| 211.33 | 1.17 | 1.17 |
| 168.26 | 1.10 | 1.10 |
| 216.31 | 2.98 | 2.98 |