Basic Information
ID: ALA4390593
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis H37Ra PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins by spectrophotometric analysis
Format: BAO_0000019
Organism: Mycobacterium tuberculosis H37Ra
Target: Phosphotyrosine protein phosphatase(ALA4295521)
Document: ALA4387790
Inhibition of Mycobacterium tuberculosis H37Ra PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins by spectrophotometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390593
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.23 | 7.23 |
| 366.55 | 5.86 | 5.86 |
| 384.56 | 5.05 | 5.05 |
| 368.56 | 5.80 | 5.80 |
| 384.56 | 5.05 | 5.05 |
| 400.56 | 4.02 | 4.02 |
| 368.56 | 5.65 | 5.65 |
| 400.56 | 4.53 | 4.53 |
| 366.55 | 5.86 | 5.86 |
| 384.56 | 5.21 | 5.21 |
| 386.58 | 5.00 | 5.00 |
| 386.58 | 4.84 | 4.84 |
| 400.56 | 4.02 | 4.02 |
| 411.59 | 4.68 | 4.68 |
| 400.56 | 4.02 | 4.02 |
| 418.57 | 3.22 | 3.22 |
| 382.54 | 5.07 | 5.07 |
| 381.56 | 4.70 | 4.70 |
| 413.60 | 4.76 | 4.76 |
| 386.58 | 5.00 | 5.00 |
| 400.56 | 4.02 | 4.02 |
| 397.56 | 4.02 | 4.02 |
| 386.58 | 4.84 | 4.84 |
| 382.54 | 5.74 | 5.74 |