Basic Information
ID: ALA4390738
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged PDI expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in enzyme-mediated bovine insulin aggregation
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4390738
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.26 | 4.31 | 4.31 |
| 254.28 | 3.30 | 3.30 |
| 240.26 | 2.99 | 2.99 |
| 240.26 | 2.99 | 2.99 |
| 263.30 | 3.46 | 3.46 |
| 263.30 | 3.46 | 3.46 |
| 293.32 | 3.47 | 3.47 |
| 292.26 | 4.31 | 4.31 |
| 240.26 | 2.99 | 2.99 |
| 292.26 | 4.31 | 4.31 |
| 267.26 | 3.30 | 3.30 |
| 252.08 | ||
| 316.40 | 4.44 | 4.44 |
| 452.44 | 3.99 | 3.99 |
| 312.35 | 2.10 | 2.10 |
| 297.27 | 3.19 | 3.19 |
| 301.35 | 4.35 | 4.35 |
| 396.51 | 4.27 | 4.27 |
| 267.26 | 3.30 | 3.30 |
| 267.26 | 3.30 | 3.30 |
| 279.30 | 3.17 | 3.17 |
| 312.32 | 3.08 | 3.08 |
| 249.27 | 3.16 | 3.16 |
| 452.62 | 5.83 | 5.83 |
| 248.28 | 3.04 | 3.04 |
| 388.45 | 4.26 | 4.26 |
| 385.47 | 4.15 | 4.15 |
| 286.26 | 3.13 | 3.13 |
| 433.45 | 4.16 | 4.16 |
| 301.35 | 4.35 | 4.35 |
| 399.49 | 4.45 | 4.45 |
| 364.42 | 4.87 | 4.87 |
| 268.27 | 2.99 | 2.99 |
| 443.61 | 5.66 | 5.66 |
| 317.27 | 4.18 | 4.18 |
| 318.38 | 3.29 | 3.29 |
| 279.30 | 3.17 | 3.17 |
| 375.22 | 3.62 | 3.62 |
| 340.38 | 4.63 | 4.63 |
| 267.28 | 2.86 | 2.86 |
| 282.30 | 3.07 | 3.07 |
| 235.25 | 2.24 | 2.24 |
| 334.22 | ||
| 277.09 | ||
| 267.26 | 3.30 | 3.30 |
| 278.23 | 3.39 | 3.39 |
| 282.30 | 3.07 | 3.07 |
| 350.29 | 4.09 | 4.09 |
| 350.40 | 4.57 | 4.57 |
| 317.27 | 4.18 | 4.18 |
| 340.40 | 2.70 | 2.70 |
| 457.59 | 4.96 | 4.96 |
| 430.48 | 2.15 | 2.15 |
| 249.27 | 3.16 | 3.16 |
| 249.27 | 3.16 | 3.16 |
| 267.26 | 3.30 | 3.30 |
| 349.41 | 4.60 | 4.60 |
| 363.44 | 4.91 | 4.91 |
| 352.42 | 2.90 | 2.90 |
| 267.26 | 3.30 | 3.30 |
| 303.16 | 4.05 | 4.05 |
| 312.17 | 4.22 | 4.22 |
| 298.29 | 3.00 | 3.00 |
| 336.26 | 4.01 | 4.01 |
| 368.46 | 3.48 | 3.48 |
| 466.47 | 4.08 | 4.08 |
| 429.54 | 4.18 | 4.18 |
| 359.45 | 3.32 | 3.32 |
| 335.40 | 4.27 | 4.27 |
| 337.38 | 3.12 | 3.12 |
| 424.57 | 5.05 | 5.05 |
| 285.71 | 4.25 | 4.25 |