Basic Information
ID: ALA4390898
Type: Binding
Description: Inhibition of HCV genotype 1b wild-type NS5B RNA dependent RNA polymerase infected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 48 hrs by steady-glo luciferase reporter gene assay
Format: BAO_0000019
Organism: Hepatitis C virus subtype 1b
Target: Hepatitis C virus NS5B RNA-dependent RNA polymerase(ALA5375)
Document: ALA4390640
Inhibition of HCV genotype 1b wild-type NS5B RNA dependent RNA polymerase infected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 48 hrs by steady-glo luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390898
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.31 | ||
| 513.33 | ||
| 514.30 | ||
| 514.30 | ||
| 576.46 | ||
| 531.74 | ||
| 562.43 | ||
| 568.82 | ||
| 488.49 | 6.31 | 6.31 |
| 514.29 | ||
| 532.31 | ||
| 514.32 | ||
| 528.32 | ||
| 562.43 | ||
| 556.81 | ||
| 590.36 | ||
| 528.35 | ||
| 532.31 | ||
| 562.43 | ||
| 540.35 | ||
| 522.36 | ||
| 513.31 | ||
| 512.35 | ||
| 604.39 | ||
| 514.32 | ||
| 522.36 |