Basic Information
ID: ALA4390899
Type: Binding
Description: Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase C316N mutant infected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 48 hrs by steady-glo luciferase reporter gene assay
Format: BAO_0000019
Organism: Hepatitis C virus subtype 1b
Target: Hepatitis C virus NS5B RNA-dependent RNA polymerase(ALA5375)
Document: ALA4390640
Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase C316N mutant infected in human HuH7 Lunet replicon cells assessed as reduction in viral replication after 48 hrs by steady-glo luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390899
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.31 | ||
| 513.33 | ||
| 514.30 | ||
| 514.30 | ||
| 576.46 | ||
| 531.74 | ||
| 562.43 | ||
| 568.82 | ||
| 488.49 | 6.31 | 6.31 |
| 514.29 | ||
| 532.31 | ||
| 514.32 | ||
| 528.32 | ||
| 562.43 | ||
| 556.81 | ||
| 590.36 | ||
| 528.35 | ||
| 532.31 | ||
| 562.43 | ||
| 540.35 | ||
| 522.36 | ||
| 513.31 | ||
| 512.35 | ||
| 604.39 | ||
| 514.32 | ||
| 522.36 |