Basic Information
ID: ALA4390975
Type: ADME
Description: Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Dihydroorotate dehydrogenase(ALA1966)
Document: ALA4390643
Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4390975
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 108.10 | 0.25 | 0.25 |
| 242.27 | 3.23 | 3.23 |
| 375.37 | 5.85 | 5.85 |
| 270.21 | 3.00 | 3.00 |
| 242.27 | 3.09 | 3.09 |
| 122.12 | 0.64 | 0.64 |
| 244.29 | 3.31 | 3.31 |
| 366.84 | 5.51 | 5.51 |
| 174.15 | 1.51 | 1.51 |
| 396.46 | 4.39 | 4.39 |
| 334.37 | 2.66 | 2.66 |
| 164.20 | 1.67 | 1.67 |
| 265.27 | 2.95 | 2.95 |
| 295.29 | 2.96 | 2.96 |
| 293.32 | 3.56 | 3.56 |
| 281.31 | 3.22 | 3.22 |
| 299.71 | 3.60 | 3.60 |
| 299.71 | 3.60 | 3.60 |
| 221.64 | 1.74 | 1.74 |
| 333.26 | 3.97 | 3.97 |
| 368.82 | 3.31 | 3.31 |
| 309.28 | 2.68 | 2.68 |
| 379.37 | 2.57 | 2.57 |
| 334.16 | 4.25 | 4.25 |
| 323.30 | 2.72 | 2.72 |
| 299.71 | 3.60 | 3.60 |
| 283.26 | 3.09 | 3.09 |
| 403.27 | 3.96 | 3.96 |