Basic Information
ID: ALA4391653
Type: Toxicity
Description: Selectivity index, ratio of Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by SRB assay to Antiviral activity against acyclovir-sensitive Herpes simplex virus 1 KOS infected in African green monkey Vero cells assessed as inhibition of viral replication after 48 hrs by naphthol blue-black staining-based plaque reduction assay
Format: BAO_0000219
Target: Unchecked(ALA612545)
Document: ALA4390653
Selectivity index, ratio of Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by SRB assay to Antiviral activity against acyclovir-sensitive Herpes simplex virus 1 KOS infected in African green monkey Vero cells assessed as inhibition of viral replication after 48 hrs by naphthol blue-black staining-based plaque reduction assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4391653
Ratio CC50/IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 225.21 | -1.33 | -1.33 |
| 374.52 | 3.60 | 3.60 |
| 617.74 | 1.39 | 1.39 |
| 431.57 | 2.72 | 2.72 |
| 785.89 | 3.68 | 3.68 |
| 779.88 | -0.78 | -0.78 |
| 450.02 | 3.97 | 3.97 |
| 617.74 | 1.39 | 1.39 |
| 494.47 | 4.12 | 4.12 |
| 505.70 | 2.69 | 2.69 |
| 785.89 | 3.68 | 3.68 |
| 531.70 | 4.71 | 4.71 |
| 617.74 | 1.39 | 1.39 |
| 574.81 | 5.61 | 5.61 |
| 474.64 | 2.31 | 2.31 |
| 541.13 | 5.49 | 5.49 |
| 785.89 | 3.68 | 3.68 |
| 1074.14 |